16257206

Source:http://linkedlifedata.com/resource/pubmed/id/16257206

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0040610, umls-concept:C0205217, umls-concept:C0243072, umls-concept:C1280500, umls-concept:C2926735
pubmed:issue	3
pubmed:dateCreated	2005-12-26
pubmed:abstractText	Tramadol is a centrally acting opioid analgesic structurally related to codeine and morphine. Analogs of tramadol with deuterium-for-hydrogen replacement at metabolically active sites were prepared and evaluated in vitro and in vivo.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9107377
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Analgesics, Opioid, http://linkedlifedata.com/resource/pubmed/chemical/Codeine, http://linkedlifedata.com/resource/pubmed/chemical/Morphine, http://linkedlifedata.com/resource/pubmed/chemical/Tramadol
pubmed:status	MEDLINE
pubmed:month	Feb
pubmed:issn	0960-894X
pubmed:author	pubmed-author:AbolinCraigC, pubmed-author:HewittMichael CMC, pubmed-author:KochPatrickP, pubmed-author:ShaoLimingL, pubmed-author:VarneyMarkM
pubmed:issnType	Print
pubmed:volume	16
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	691-4
pubmed:meshHeading	pubmed-meshheading:16257206-Analgesics, Opioid, pubmed-meshheading:16257206-Animals, pubmed-meshheading:16257206-Binding Sites, pubmed-meshheading:16257206-Codeine, pubmed-meshheading:16257206-Models, Chemical, pubmed-meshheading:16257206-Morphine, pubmed-meshheading:16257206-Pain, pubmed-meshheading:16257206-Rats, pubmed-meshheading:16257206-Time Factors, pubmed-meshheading:16257206-Tramadol
pubmed:year	2006
pubmed:articleTitle	Derivatives of tramadol for increased duration of effect.
pubmed:affiliation	Sepracor Inc., 84 Waterford Drive, Marlborough, MA 01752, USA. liming.shao@sepracor.com
pubmed:publicationType	Journal Article