Linked Life Data

16254698

Source:http://linkedlifedata.com/resource/pubmed/id/16254698

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2005-10-28
pubmed:abstractText
Multiple sclerosis has long been recognized as a multifocal inflammatory demyelinating disease of the central nervous system. The fact that patients with multiple sclerosis can develop a secondary progressive phase of their disease which is resistant to anti-inflammatory therapies, together with the fact that brain atrophy can develop in patients with a relatively low volume of white matter lesions, has led to suggestions that multiple sclerosis may be a degenerative disease. However, primary degenerative disorders are not usually associated with recurrent episodes of inflammatory demyelination. Support for neurodegeneration in MS being associated with focal lesions comes from topographical mapping of the spatial relationship of axonal injury and tissue loss to lesions using advanced image analysis methods.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0340-5354
pubmed:author
pubmed:issnType
Print
pubmed:volume
252 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
v25-9
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Changes observed in multiple sclerosis using magnetic resonance imaging reflect a focal pathology distributed along axonal pathways.
pubmed:affiliation
Montreal Neurological Institute and Dept. of Neurology and Neurosurgery, McGill University, 301 University St., Montreal, Quebec, Canada H3A 2B4. doug@mrs.mni.mcgill.ca
pubmed:publicationType
Journal Article, Review