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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1992-8-13
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pubmed:abstractText |
We evaluated the effect of captopril treatment on left ventricular mass (LVM) and function in sustained mild-to-moderate primary hypertension. In 16 men aged 34.5 +/- 6.4 yrs. M-mode echo and pulsed wave Doppler recordings were obtained prior to and after 2 months captopril treatment (50-150 mg daily). No significant changes in heart rate, systolic blood pressure, ejection fraction, fractional shortening, cardiac output, LVM and Doppler-derived indices of mitral inflow were observed. Diastolic blood pressure measured during examination fell from 102.2 +/- 13.3 to 90.3 +/- 9 mmHg (p less than 0.026). No consistent correlations between catecholamines and indexes of left ventricular function were found. Two-month captopril therapy in mild-to-moderate hypertension results in diastolic blood pressure lowering with no effect on LVM or left ventricular function.
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pubmed:language |
pol
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0022-9032
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
36
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
267-71
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1625407-Adult,
pubmed-meshheading:1625407-Captopril,
pubmed-meshheading:1625407-Catecholamines,
pubmed-meshheading:1625407-Echocardiography, Doppler,
pubmed-meshheading:1625407-Humans,
pubmed-meshheading:1625407-Hypertension,
pubmed-meshheading:1625407-Male,
pubmed-meshheading:1625407-Renin,
pubmed-meshheading:1625407-Ventricular Function, Left
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pubmed:year |
1992
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pubmed:articleTitle |
[Primary arterial hypertension. Treatment with captopril and function of the left heart ventricle, concentration of catecholamine in blood and activity of renin].
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pubmed:affiliation |
Kliniki Nadci?nienia Tetniczego i Chorób Naczy? Instytutu Chorób Wewnetrznych Akademii Medycznej, Warszawie.
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pubmed:publicationType |
Journal Article,
English Abstract,
Research Support, Non-U.S. Gov't
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