Linked Life Data

16248275

Source:http://linkedlifedata.com/resource/pubmed/id/16248275

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 Suppl
pubmed:dateCreated
2005-10-26
pubmed:abstractText
With the approval of interventions or treatments for periodontal disease based on results of large clinical trials, it is often difficult for the clinician to determine whether the statistical results obtained from these studies are clinically significant and whether these interventions or treatments will thus be effective in their individual patients. In this article, a series of measures of clinical significance are derived from the literature, and a 2-step approach is suggested for determining clinical significance. First, the reliability of the data as a function of the reliability of the measurement tool(s) is calculated, and then clinical significance is put into the context of effect size. By using these estimators, clinicians can determine, for example, whether administration of an experimental local medication plus scaling and root planing provides a clinically significant outcome, which can assist them in deciding which interventions are most effective for their patients.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1466-2094
pubmed:author
pubmed:issnType
Print
pubmed:volume
7
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-6
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
The clinical significance of new therapies for the management of periodontal disease.
pubmed:affiliation
Boston University Goldman School of Dental Medicine, 100 E Newton Street, Boston, MA 02118, USA. tvandyke@bu.edu
pubmed:publicationType
Journal Article