|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
34
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|
pubmed:dateCreated |
2005-11-29
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|
pubmed:abstractText |
Epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors have demonstrated antitumor activity in patients with non-small-cell lung cancer (NSCLC). This study examined the safety profile of the monoclonal antibody EGFR inhibitor, cetuximab, when added to paclitaxel and carboplatin in untreated patients with stage IV NSCLC. Secondary objectives included efficacy and paclitaxel and carboplatin pharmacokinetics during cetuximab treatment.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Dec
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pubmed:issn |
0732-183X
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
23
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pubmed:owner |
NLM
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|
pubmed:authorsComplete |
Y
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pubmed:pagination |
8786-93
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16246975-Adult,
pubmed-meshheading:16246975-Aged,
pubmed-meshheading:16246975-Antibodies, Monoclonal,
pubmed-meshheading:16246975-Antineoplastic Combined Chemotherapy Protocols,
pubmed-meshheading:16246975-Area Under Curve,
pubmed-meshheading:16246975-Carboplatin,
pubmed-meshheading:16246975-Carcinoma, Non-Small-Cell Lung,
pubmed-meshheading:16246975-Dose-Response Relationship, Drug,
pubmed-meshheading:16246975-Exanthema,
pubmed-meshheading:16246975-Fatigue,
pubmed-meshheading:16246975-Female,
pubmed-meshheading:16246975-Follow-Up Studies,
pubmed-meshheading:16246975-Humans,
pubmed-meshheading:16246975-Immunohistochemistry,
pubmed-meshheading:16246975-Lung Neoplasms,
pubmed-meshheading:16246975-Male,
pubmed-meshheading:16246975-Middle Aged,
pubmed-meshheading:16246975-Neoplasm Staging,
pubmed-meshheading:16246975-Paclitaxel,
pubmed-meshheading:16246975-Receptor, Epidermal Growth Factor,
pubmed-meshheading:16246975-Survival Analysis,
pubmed-meshheading:16246975-Time Factors,
pubmed-meshheading:16246975-Treatment Outcome
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Multicenter phase I/II study of cetuximab with paclitaxel and carboplatin in untreated patients with stage IV non-small-cell lung cancer.
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|
pubmed:affiliation |
Division of Medical Oncology and Department of Pharmaceutical Sciences, University of Colorado Health Sciences Center, Aurora, CO 80010, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Multicenter Study,
Clinical Trial, Phase II,
Clinical Trial, Phase I
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