16245069

Source:http://linkedlifedata.com/resource/pubmed/id/16245069

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0019564, umls-concept:C0027882, umls-concept:C0028040, umls-concept:C0678558, umls-concept:C0814002, umls-concept:C1280500
pubmed:issue	11
pubmed:dateCreated	2005-10-24
pubmed:abstractText	To study nicotine's effects on neurogenesis in the dentate gyrus of the hippocampus, nicotine was injected intraperitoneally into adult rats. After sacrificing, the hippocampal formation was processed for immunohistochemical staining of PSA-NCAM, NeuN and GFAP. Nicotine decreased numbers of PSA-NCAM(+) and NeuN(+) cells dose-dependently.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9702341
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Biological Markers, http://linkedlifedata.com/resource/pubmed/chemical/Glial Fibrillary Acidic Protein, http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins, http://linkedlifedata.com/resource/pubmed/chemical/NeuN protein, mouse, http://linkedlifedata.com/resource/pubmed/chemical/Neural Cell Adhesion Molecule L1, http://linkedlifedata.com/resource/pubmed/chemical/Nicotine, http://linkedlifedata.com/resource/pubmed/chemical/Nicotinic Agonists, http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Proteins, http://linkedlifedata.com/resource/pubmed/chemical/Sialic Acids, http://linkedlifedata.com/resource/pubmed/chemical/polysialyl neural cell adhesion...
pubmed:status	MEDLINE
pubmed:month	Nov
pubmed:issn	0300-9564
pubmed:author	pubmed-author:KitoSS, pubmed-author:ShingoA SAS
pubmed:issnType	Print
pubmed:volume	112
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1475-8
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:16245069-Animals, pubmed-meshheading:16245069-Biological Markers, pubmed-meshheading:16245069-Cell Count, pubmed-meshheading:16245069-Cell Differentiation, pubmed-meshheading:16245069-Cell Division, pubmed-meshheading:16245069-Cell Proliferation, pubmed-meshheading:16245069-Dentate Gyrus, pubmed-meshheading:16245069-Dose-Response Relationship, Drug, pubmed-meshheading:16245069-Down-Regulation, pubmed-meshheading:16245069-Glial Fibrillary Acidic Protein, pubmed-meshheading:16245069-Hippocampus, pubmed-meshheading:16245069-Immunohistochemistry, pubmed-meshheading:16245069-Injections, Intraperitoneal, pubmed-meshheading:16245069-Male, pubmed-meshheading:16245069-Nerve Tissue Proteins, pubmed-meshheading:16245069-Neural Cell Adhesion Molecule L1, pubmed-meshheading:16245069-Neuronal Plasticity, pubmed-meshheading:16245069-Neurons, pubmed-meshheading:16245069-Nicotine, pubmed-meshheading:16245069-Nicotinic Agonists, pubmed-meshheading:16245069-Nuclear Proteins, pubmed-meshheading:16245069-Rats, pubmed-meshheading:16245069-Rats, Inbred BB, pubmed-meshheading:16245069-Sialic Acids, pubmed-meshheading:16245069-Stem Cells
pubmed:year	2005
pubmed:articleTitle	Effects of nicotine on neurogenesis and plasticity of hippocampal neurons.
pubmed:affiliation	Hyogo University School of Health Sciences, Hyogo, Japan. ashingo@hyogo-dai.ac.jp
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't