Source:http://linkedlifedata.com/resource/pubmed/id/16244492
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2006-2-21
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pubmed:abstractText |
Inherited thrombophilias are associated with an increased risk of maternal thromboembolism and certain adverse pregnancy outcomes, including second- and third-trimester fetal loss, placental abruption, severe intrauterine growth restriction, and early-onset, severe preeclampsia. Pregnant patients with severe thrombophilias, especially antithrombinopathies are at very high risk for both thromboembolism and adverse pregnancy outcomes. A case of a patient with antithrombin deficiency is reported, who had two successful pregnancies after eight miscarriages. Our case shows that a combined treatment with antithrombin substitution and a prophylactic, body-weight-adjusted dose of low-molecular-weight heparin may be successful in preventing pregnancy loss and thromboembolism in antithrombin deficiency during pregnancy, although other complications, such as preeclampsia and intrauterine growth restriction cannot always be prevented.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0378-7346
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pubmed:author | |
pubmed:copyrightInfo |
Copyright 2006 S. Karger AG, Basel.
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pubmed:issnType |
Print
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
111-4
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pubmed:meshHeading |
pubmed-meshheading:16244492-Abortion, Habitual,
pubmed-meshheading:16244492-Adult,
pubmed-meshheading:16244492-Anticoagulants,
pubmed-meshheading:16244492-Female,
pubmed-meshheading:16244492-Fibrin,
pubmed-meshheading:16244492-Heparin,
pubmed-meshheading:16244492-Humans,
pubmed-meshheading:16244492-Infertility, Female,
pubmed-meshheading:16244492-Pregnancy,
pubmed-meshheading:16244492-Pregnancy Complications, Hematologic,
pubmed-meshheading:16244492-Thromboembolism,
pubmed-meshheading:16244492-Thrombophilia,
pubmed-meshheading:16244492-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Two successful pregnancies following eight miscarriages in a patient with antithrombin deficiency.
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pubmed:affiliation |
Department of Obstetrics and Gynecology, University of Pécs, Pécs, Hungary. andras.szilagyi@aok.pte.hu
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pubmed:publicationType |
Journal Article,
Case Reports
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