Linked Life Data

16243825

Source:http://linkedlifedata.com/resource/pubmed/id/16243825

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
20
pubmed:dateCreated
2005-10-24
pubmed:abstractText
BRCA2, FANCC, and FANCG gene mutations are present in a subset of pancreatic cancer. Defects in these genes could lead to hypersensitivity to interstrand cross-linkers in vivo and a more optimal treatment of pancreatic cancer patients based on the genetic profile of the tumor.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antineoplastic Agents, http://linkedlifedata.com/resource/pubmed/chemical/BRCA2 Protein, http://linkedlifedata.com/resource/pubmed/chemical/Caspases, http://linkedlifedata.com/resource/pubmed/chemical/Chlorambucil, http://linkedlifedata.com/resource/pubmed/chemical/Cisplatin, http://linkedlifedata.com/resource/pubmed/chemical/Cross-Linking Reagents, http://linkedlifedata.com/resource/pubmed/chemical/Deoxycytidine, http://linkedlifedata.com/resource/pubmed/chemical/Doxorubicin, http://linkedlifedata.com/resource/pubmed/chemical/Etoposide, http://linkedlifedata.com/resource/pubmed/chemical/FANCC protein, human, http://linkedlifedata.com/resource/pubmed/chemical/FANCG protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Fanconi Anemia Complementation..., http://linkedlifedata.com/resource/pubmed/chemical/Fanconi Anemia Complementation..., http://linkedlifedata.com/resource/pubmed/chemical/Fanconi Anemia Complementation..., http://linkedlifedata.com/resource/pubmed/chemical/Fluorouracil, http://linkedlifedata.com/resource/pubmed/chemical/Melphalan, http://linkedlifedata.com/resource/pubmed/chemical/Mitomycin, http://linkedlifedata.com/resource/pubmed/chemical/Paclitaxel, http://linkedlifedata.com/resource/pubmed/chemical/Vinblastine, http://linkedlifedata.com/resource/pubmed/chemical/gemcitabine
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
7508-15
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed-meshheading:16243825-Animals, pubmed-meshheading:16243825-Antineoplastic Agents, pubmed-meshheading:16243825-Apoptosis, pubmed-meshheading:16243825-BRCA2 Protein, pubmed-meshheading:16243825-Caspases, pubmed-meshheading:16243825-Cell Cycle, pubmed-meshheading:16243825-Cell Line, Tumor, pubmed-meshheading:16243825-Cell Survival, pubmed-meshheading:16243825-Chlorambucil, pubmed-meshheading:16243825-Cisplatin, pubmed-meshheading:16243825-Cross-Linking Reagents, pubmed-meshheading:16243825-Deoxycytidine, pubmed-meshheading:16243825-Dose-Response Relationship, Drug, pubmed-meshheading:16243825-Doxorubicin, pubmed-meshheading:16243825-Etoposide, pubmed-meshheading:16243825-Fanconi Anemia Complementation Group C Protein, pubmed-meshheading:16243825-Fanconi Anemia Complementation Group G Protein, pubmed-meshheading:16243825-Fanconi Anemia Complementation Group Proteins, pubmed-meshheading:16243825-Female, pubmed-meshheading:16243825-Fluorouracil, pubmed-meshheading:16243825-Humans, pubmed-meshheading:16243825-Inhibitory Concentration 50, pubmed-meshheading:16243825-Melphalan, pubmed-meshheading:16243825-Mice, pubmed-meshheading:16243825-Mice, Nude, pubmed-meshheading:16243825-Mitomycin, pubmed-meshheading:16243825-Mutation, pubmed-meshheading:16243825-Paclitaxel, pubmed-meshheading:16243825-Pancreatic Neoplasms, pubmed-meshheading:16243825-Time Factors, pubmed-meshheading:16243825-Vinblastine, pubmed-meshheading:16243825-Xenograft Model Antitumor Assays
pubmed:year
2005
pubmed:articleTitle
In vivo therapeutic responses contingent on Fanconi anemia/BRCA2 status of the tumor.
pubmed:affiliation
Department of Oncology, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural