16243813

Source:http://linkedlifedata.com/resource/pubmed/id/16243813

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0026056, umls-concept:C0031327, umls-concept:C0059563, umls-concept:C0182400, umls-concept:C0205214, umls-concept:C0205419, umls-concept:C1176140, umls-concept:C1280500, umls-concept:C1285572, umls-concept:C1314763, umls-concept:C1413882, umls-concept:C1516213
pubmed:issue	20
pubmed:dateCreated	2005-10-24
pubmed:abstractText	To evaluate the effect of naturally occurring variants in genes encoding the cytochrome P450 (CYP) isoforms CYP3A4 and CYP3A5 in patients with cancer receiving midazolam as a phenotyping probe.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/N01-CO-12400
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9502500
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/ABCB10 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/ATP-Binding Cassette Transporters, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A4 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/CYP3A5 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 CYP3A, http://linkedlifedata.com/resource/pubmed/chemical/Cytochrome P-450 Enzyme System, http://linkedlifedata.com/resource/pubmed/chemical/Midazolam
pubmed:status	MEDLINE
pubmed:month	Oct
pubmed:issn	1078-0432
pubmed:author	pubmed-author:AhnDanielleD, pubmed-author:BakerSharyn DSD, pubmed-author:BatesSusan ESE, pubmed-author:CusatisGeorgeG, pubmed-author:FiggWilliam DWD, pubmed-author:IngersollRoxann GRG, pubmed-author:LepperErin RER, pubmed-author:MathijssenRon H JRH, pubmed-author:PermenterMattM, pubmed-author:PriceDouglas KDK, pubmed-author:RiesNicoleN, pubmed-author:SchenkPaul WPW, pubmed-author:SmithNicola FNF, pubmed-author:SparreboomAlexA, pubmed-author:VerweijJaapJ, pubmed-author:van SchaikRon H NRH
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	7398-404
pubmed:dateRevised	2008-11-21
pubmed:meshHeading	pubmed-meshheading:16243813-ATP-Binding Cassette Transporters, pubmed-meshheading:16243813-Adult, pubmed-meshheading:16243813-Aged, pubmed-meshheading:16243813-Alleles, pubmed-meshheading:16243813-Area Under Curve, pubmed-meshheading:16243813-Cytochrome P-450 CYP3A, pubmed-meshheading:16243813-Cytochrome P-450 Enzyme System, pubmed-meshheading:16243813-Female, pubmed-meshheading:16243813-Gene Frequency, pubmed-meshheading:16243813-Genotype, pubmed-meshheading:16243813-Humans, pubmed-meshheading:16243813-Linkage Disequilibrium, pubmed-meshheading:16243813-Male, pubmed-meshheading:16243813-Midazolam, pubmed-meshheading:16243813-Middle Aged, pubmed-meshheading:16243813-Neoplasms, pubmed-meshheading:16243813-Phenotype, pubmed-meshheading:16243813-Polymorphism, Single Nucleotide
pubmed:year	2005
pubmed:articleTitle	Effect of common CYP3A4 and CYP3A5 variants on the pharmacokinetics of the cytochrome P450 3A phenotyping probe midazolam in cancer patients.
pubmed:affiliation	Science Applications International Corporation-Frederick, Maryland, USA.
pubmed:publicationType	Journal Article, Clinical Trial, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural