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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1992-8-11
|
| pubmed:abstractText |
Sixty-eight patients with disabling episodes of inducible supraventricular tachyarrhythmia were tested electropharmacologically by transoesophageal atrial pacing. Using this technique we induced clinical arrhythmia in 67 (98.5%); 26 (38.8%) had a reciprocating tachycardia due to AV node reentry and 41 (61.2%) a by-pass tract. In the latter we induced a reciprocating tachycardia in 12 (29.3%), atrial fibrillation in 25 (36.5%) and both in 14 (34.2%). We then performed an anti-arrhythmic drug test and a transoesophageal reevaluation either after acute intravenous drug administration or during oral steady state. Altogether we tested 111 drugs or a combination of drugs before the results were considered positive; all patients tolerated the procedure well and were discharged with the drug or combination of drugs judged effective. At follow-up of 16.6 +/- 8.5 months, 42 patients (62.7%) were symptom-free, 17 (25.3%) had minor and non-disabling relapses, six (9%) stopped the drug because of inefficacy (1-1.5%) or side effects (5-7.5%); two (3%) dropped out. We conclude that electropharmacological testing with transoesophageal pacing constitutes a very good approach for inducible supraventricular tachyarrhythmias: it permits selection of optimal long-term anti-arrhythmic treatment and is well tolerated, only slightly invasive and without adverse effects.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0195-668X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
13
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
763-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:1623864-Administration, Oral,
pubmed-meshheading:1623864-Adolescent,
pubmed-meshheading:1623864-Adult,
pubmed-meshheading:1623864-Aged,
pubmed-meshheading:1623864-Anti-Arrhythmia Agents,
pubmed-meshheading:1623864-Cardiac Pacing, Artificial,
pubmed-meshheading:1623864-Drug Combinations,
pubmed-meshheading:1623864-Esophagus,
pubmed-meshheading:1623864-Female,
pubmed-meshheading:1623864-Heart Atria,
pubmed-meshheading:1623864-Humans,
pubmed-meshheading:1623864-Injections, Intravenous,
pubmed-meshheading:1623864-Male,
pubmed-meshheading:1623864-Middle Aged,
pubmed-meshheading:1623864-Tachycardia, Supraventricular
|
| pubmed:year |
1992
|
| pubmed:articleTitle |
Electropharmacological testing by transoesophageal atrial pacing in inducible supraventricular tachyarrhythmias. A good approach for selection of long-term anti-arrhythmic therapy.
|
| pubmed:affiliation |
Divisione di Cardiologia, Ospedale S. Chiara, Trento, Italy.
|
| pubmed:publicationType |
Journal Article
|