Source:http://linkedlifedata.com/resource/pubmed/id/16238470
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2005-10-21
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pubmed:abstractText |
In this study we investigated the effect of beta-glucan derived from Saccharomyces cerevisiae on fungicidal activity, cytokine production and natural killer activity. Spleen and peritoneal cells from female C57BL/6 mice, previously injected (24 or 48 h) with 20 or 100 microg of glucan by i.p. route, were assayed. In vivo beta-glucan administration primed spleen cells for a higher production of IL-12 and TNF-alpha when S. aureus was used as a stimulus. In addition, beta-glucan increased NK spleen cells activity against YAC target cells. Some immunomodulatory activities not yet described for beta-glucan were observed in this work.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0862-8408
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
557-64
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pubmed:dateRevised |
2008-4-2
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pubmed:meshHeading |
pubmed-meshheading:16238470-Animals,
pubmed-meshheading:16238470-Antifungal Agents,
pubmed-meshheading:16238470-Cytokines,
pubmed-meshheading:16238470-Dose-Response Relationship, Drug,
pubmed-meshheading:16238470-Female,
pubmed-meshheading:16238470-Immunologic Factors,
pubmed-meshheading:16238470-Killer Cells, Natural,
pubmed-meshheading:16238470-Mice,
pubmed-meshheading:16238470-Mice, Inbred C57BL,
pubmed-meshheading:16238470-Paracoccidioides,
pubmed-meshheading:16238470-Saccharomyces cerevisiae,
pubmed-meshheading:16238470-beta-Glucans
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pubmed:year |
2005
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pubmed:articleTitle |
Immunomodulatory activities associated with beta-glucan derived from Saccharomyces cerevisiae.
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pubmed:affiliation |
Department of Microbiology and Immunology, Institute of Biosciences, State University of Sao Paulo, Sao Paulo, Brasil.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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