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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-10-19
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pubmed:abstractText |
We studied the interaction between VEGF and BMP2 during bone formation and bone healing. Results indicate that VEGF antagonist inhibited BMP2-elicited bone formation, whereas the delivery of exogenous VEGF enhanced BMP2-induced bone formation and bone healing through modulation of angiogenesis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, CD31,
http://linkedlifedata.com/resource/pubmed/chemical/Bmp2 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Protein 2,
http://linkedlifedata.com/resource/pubmed/chemical/Bone Morphogenetic Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type II,
http://linkedlifedata.com/resource/pubmed/chemical/Collagen Type X,
http://linkedlifedata.com/resource/pubmed/chemical/FLT1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9,
http://linkedlifedata.com/resource/pubmed/chemical/Mmp9 protein, mouse,
http://linkedlifedata.com/resource/pubmed/chemical/Transforming Growth Factor beta,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor A,
http://linkedlifedata.com/resource/pubmed/chemical/Vascular Endothelial Growth Factor...
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0884-0431
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
20
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2017-27
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16234975-Animals,
pubmed-meshheading:16234975-Antigens, CD31,
pubmed-meshheading:16234975-Bone Morphogenetic Protein 2,
pubmed-meshheading:16234975-Bone Morphogenetic Proteins,
pubmed-meshheading:16234975-Collagen Type II,
pubmed-meshheading:16234975-Collagen Type X,
pubmed-meshheading:16234975-Fracture Healing,
pubmed-meshheading:16234975-Genetic Vectors,
pubmed-meshheading:16234975-Immunohistochemistry,
pubmed-meshheading:16234975-Male,
pubmed-meshheading:16234975-Matrix Metalloproteinase 9,
pubmed-meshheading:16234975-Mice,
pubmed-meshheading:16234975-Mice, Inbred C57BL,
pubmed-meshheading:16234975-Muscle, Skeletal,
pubmed-meshheading:16234975-Neovascularization, Physiologic,
pubmed-meshheading:16234975-Osteogenesis,
pubmed-meshheading:16234975-Skull,
pubmed-meshheading:16234975-Stem Cell Transplantation,
pubmed-meshheading:16234975-Stem Cells,
pubmed-meshheading:16234975-Transfection,
pubmed-meshheading:16234975-Transforming Growth Factor beta,
pubmed-meshheading:16234975-Vascular Endothelial Growth Factor A,
pubmed-meshheading:16234975-Vascular Endothelial Growth Factor Receptor-1
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pubmed:year |
2005
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pubmed:articleTitle |
VEGF improves, whereas sFlt1 inhibits, BMP2-induced bone formation and bone healing through modulation of angiogenesis.
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pubmed:affiliation |
Growth and Development Laboratory, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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