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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
2006-1-10
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pubmed:abstractText |
The sodium iodide symporter (NIS) mediates the active iodide uptake in the thyroid gland as well as lactating breast tissue. Recently induction of functional NIS expression was reported in the estrogen receptor-positive human breast cancer cell line MCF-7 by all-trans retinoic acid (atRA) treatment in vitro and in vivo, which might offer the potential to treat breast cancer with radioiodine.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0021-972X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
69-78
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16234306-Blotting, Northern,
pubmed-meshheading:16234306-Blotting, Western,
pubmed-meshheading:16234306-Breast Neoplasms,
pubmed-meshheading:16234306-Cell Line, Tumor,
pubmed-meshheading:16234306-Cell Membrane,
pubmed-meshheading:16234306-Cell Survival,
pubmed-meshheading:16234306-Dexamethasone,
pubmed-meshheading:16234306-Female,
pubmed-meshheading:16234306-Humans,
pubmed-meshheading:16234306-Immunohistochemistry,
pubmed-meshheading:16234306-Iodides,
pubmed-meshheading:16234306-Iodine Radioisotopes,
pubmed-meshheading:16234306-RNA, Messenger,
pubmed-meshheading:16234306-Receptors, Estrogen,
pubmed-meshheading:16234306-Symporters,
pubmed-meshheading:16234306-Tretinoin,
pubmed-meshheading:16234306-Tumor Stem Cell Assay
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pubmed:year |
2006
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pubmed:articleTitle |
Dexamethasone stimulation of retinoic Acid-induced sodium iodide symporter expression and cytotoxicity of 131-I in breast cancer cells.
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pubmed:affiliation |
Department of Internal Medicine II, Ludwig-Maximilians-University, 81377 Munich, Germany.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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