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pubmed-article:16225913pubmed:abstractTextWe have previously shown that adenoviral-mediated melanoma differentiation-associated gene-7 (Ad.mda-7) therapy induces apoptosis in ovarian cancer cells. However, the apoptosis induction was low and directly correlated with infectivity of Ad.mda-7. The objective of this study was to derive ovarian cancer targeted infectivity-enhanced adenoviral vectors encoding mda-7 and evaluate their enhancement in therapeutic efficacy for ovarian carcinoma.lld:pubmed
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pubmed-article:16225913pubmed:articleTitleOvarian cancer targeted adenoviral-mediated mda-7/IL-24 gene therapy.lld:pubmed
pubmed-article:16225913pubmed:affiliationDivision of Human Gene Therapy, Department of Medicine, University of Alabama at Birmingham, AL 35294, USA. param@uab.edulld:pubmed
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