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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
11
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pubmed:dateCreated |
2005-10-17
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pubmed:abstractText |
To elucidate the involvement of the endothelin (ET) pathway in the pathogenesis of monocrotaline (MCT)-induced pulmonary arterial hypertension (PAH) and the therapeutic effect of CPU 86017 (p-chlorobenzyltetrahydroberberine chloride) in rats.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1671-4083
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1309-16
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pubmed:meshHeading |
pubmed-meshheading:16225752-Animals,
pubmed-meshheading:16225752-Berberine,
pubmed-meshheading:16225752-Blood Pressure,
pubmed-meshheading:16225752-Calcium Channel Blockers,
pubmed-meshheading:16225752-Endothelin-1,
pubmed-meshheading:16225752-Hypertension, Pulmonary,
pubmed-meshheading:16225752-Lung,
pubmed-meshheading:16225752-Male,
pubmed-meshheading:16225752-Monocrotaline,
pubmed-meshheading:16225752-Nitric Oxide,
pubmed-meshheading:16225752-Nitric Oxide Synthase Type II,
pubmed-meshheading:16225752-Nitric Oxide Synthase Type III,
pubmed-meshheading:16225752-RNA, Messenger,
pubmed-meshheading:16225752-Rats,
pubmed-meshheading:16225752-Rats, Sprague-Dawley,
pubmed-meshheading:16225752-Vasoconstriction
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pubmed:year |
2005
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pubmed:articleTitle |
CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathway.
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pubmed:affiliation |
Research Division of Pharmacology, China Pharmaceutical University, Nanjing 210009, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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