Source:http://linkedlifedata.com/resource/pubmed/id/16224570
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-10-14
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pubmed:abstractText |
The inotropic response of the myocardium to extrasystolic treatment was studied on isolated perfused papillary muscles from rats with postinfarction cardiosclerosis. The development of postinfarction cardiosclerosis was accompanied by a decrease in myocardial excitability. The amplitude of extrasystolic contractions in the remodeled myocardium far surpassed the control. However, the amplitude of postextrasystolic contraction did not surpass that in normal contraction-relaxation cycle. Our results suggest that the ability of the sarcoplasmic reticulum in cardiomyocytes to accumulate Ca2+ is impaired during postinfarction remodeling.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0007-4888
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
647-50
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16224570-Animals,
pubmed-meshheading:16224570-Anti-Arrhythmia Agents,
pubmed-meshheading:16224570-Calcium,
pubmed-meshheading:16224570-Electric Stimulation,
pubmed-meshheading:16224570-Heart Ventricles,
pubmed-meshheading:16224570-Isometric Contraction,
pubmed-meshheading:16224570-Male,
pubmed-meshheading:16224570-Myocardial Contraction,
pubmed-meshheading:16224570-Myocardial Ischemia,
pubmed-meshheading:16224570-Myocardium,
pubmed-meshheading:16224570-Myocytes, Cardiac,
pubmed-meshheading:16224570-Papillary Muscles,
pubmed-meshheading:16224570-Perfusion,
pubmed-meshheading:16224570-Rats,
pubmed-meshheading:16224570-Rats, Wistar,
pubmed-meshheading:16224570-Sarcoplasmic Reticulum,
pubmed-meshheading:16224570-Systole
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pubmed:year |
2005
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pubmed:articleTitle |
Inotropic response of the myocardium in rats with postinfarction cardiosclerosis exposed to extrasystolic treatment.
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pubmed:affiliation |
Institute of Cardiology, Tomsk Research Center, Siberian Division of the Russian Academy of Medical Sciences, Tomsk, Russia. ugdina@mail.ru
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pubmed:publicationType |
Journal Article,
Comparative Study
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