Linked Life Data

16224086

Source:http://linkedlifedata.com/resource/pubmed/id/16224086

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
11
pubmed:dateCreated
2005-10-27
pubmed:abstractText
Most large, randomized phase III efficacy trials of therapeutic agents in ischemic stroke have failed to find treatment benefit. We determined whether some phase III studies could have been avoided if preceded by smaller single-arm phase II studies to evaluate the futility of proceeding to phase III.
pubmed:grant
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1524-4628
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
36
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
2410-4
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Applying a phase II futility study design to therapeutic stroke trials.
pubmed:affiliation
Department of Biostatistics, Bioinformatics & Epidemiology, Medical University of South Carolina, P.O. Box 250835, Charleston, SC 29425, USA. paleschy@musc.edu
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Randomized Controlled Trial, Clinical Trial, Phase III, Research Support, N.I.H., Extramural