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rdf:type |
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lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0087111,
umls-concept:C0185117,
umls-concept:C0205250,
umls-concept:C0360714,
umls-concept:C0392756,
umls-concept:C0535298,
umls-concept:C0597357,
umls-concept:C1332814,
umls-concept:C1439296,
umls-concept:C1956346,
umls-concept:C2911684
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pubmed:issue |
12
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pubmed:dateCreated |
2005-11-24
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pubmed:abstractText |
Recent data derived primarily from studies in animal models suggest that fractalkine (CX3CL1) and its cognate receptor, CX3CR1, play a role in atherogenesis. We, therefore, hypothesized that enhanced CX3CL1/CX3CR1 expression may promote atherogenesis in patients with coronary artery disease (CAD).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/CX3CL1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/CX3CR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CX3CL1,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokines, CX3C,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Heptanoic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Hydroxymethylglutaryl-CoA...,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-8,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Pyrroles,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Chemokine,
http://linkedlifedata.com/resource/pubmed/chemical/Simvastatin,
http://linkedlifedata.com/resource/pubmed/chemical/atorvastatin
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1524-4636
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2567-72
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16224053-Angina, Unstable,
pubmed-meshheading:16224053-Cell Adhesion,
pubmed-meshheading:16224053-Cells, Cultured,
pubmed-meshheading:16224053-Chemokine CX3CL1,
pubmed-meshheading:16224053-Chemokines, CX3C,
pubmed-meshheading:16224053-Chemotaxis,
pubmed-meshheading:16224053-Cholesterol, LDL,
pubmed-meshheading:16224053-Coronary Artery Disease,
pubmed-meshheading:16224053-Endothelium, Vascular,
pubmed-meshheading:16224053-Gene Expression,
pubmed-meshheading:16224053-Heptanoic Acids,
pubmed-meshheading:16224053-Humans,
pubmed-meshheading:16224053-Hydroxymethylglutaryl-CoA Reductase Inhibitors,
pubmed-meshheading:16224053-Interleukin-8,
pubmed-meshheading:16224053-Leukocytes, Mononuclear,
pubmed-meshheading:16224053-Membrane Proteins,
pubmed-meshheading:16224053-Myocardial Infarction,
pubmed-meshheading:16224053-Pyrroles,
pubmed-meshheading:16224053-Receptors, Chemokine,
pubmed-meshheading:16224053-Simvastatin,
pubmed-meshheading:16224053-Umbilical Veins
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pubmed:year |
2005
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pubmed:articleTitle |
Expression of fractalkine (CX3CL1) and its receptor, CX3CR1, is elevated in coronary artery disease and is reduced during statin therapy.
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pubmed:affiliation |
Department of Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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