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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2005-10-13
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pubmed:abstractText |
At 8 weeks, Buffalo/Mna rats spontaneously develop a nephrotic syndrome associated with focal segmental glomerulosclerosis (FSGS). We have previously demonstrated that this glomerulopathy recurs after renal transplantation, thus supporting the relevance of this rat model to human idiopathic nephrotic syndrome [1]. In this study, we describe renal immune abnormalities which appear in parallel to the initiation and progression of the spontaneous Buffalo/Mna nephropathy.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Ccl2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL2,
http://linkedlifedata.com/resource/pubmed/chemical/Chemokine CCL5,
http://linkedlifedata.com/resource/pubmed/chemical/Interferon-gamma,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-10,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-12,
http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-2,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/Tumor Necrosis Factor-alpha
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0085-2538
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2079-90
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16221207-Animals,
pubmed-meshheading:16221207-Chemokine CCL2,
pubmed-meshheading:16221207-Chemokine CCL5,
pubmed-meshheading:16221207-Female,
pubmed-meshheading:16221207-Gene Expression,
pubmed-meshheading:16221207-Glomerulosclerosis, Focal Segmental,
pubmed-meshheading:16221207-Interferon-gamma,
pubmed-meshheading:16221207-Interleukin-10,
pubmed-meshheading:16221207-Interleukin-12,
pubmed-meshheading:16221207-Interleukin-2,
pubmed-meshheading:16221207-Kidney,
pubmed-meshheading:16221207-Macrophages,
pubmed-meshheading:16221207-Male,
pubmed-meshheading:16221207-Nephrotic Syndrome,
pubmed-meshheading:16221207-RNA, Messenger,
pubmed-meshheading:16221207-Rats,
pubmed-meshheading:16221207-Rats, Inbred BUF,
pubmed-meshheading:16221207-Th2 Cells,
pubmed-meshheading:16221207-Tumor Necrosis Factor-alpha
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pubmed:year |
2005
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pubmed:articleTitle |
Renal macrophage activation and Th2 polarization precedes the development of nephrotic syndrome in Buffalo/Mna rats.
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pubmed:affiliation |
Institut National de la Santé Et de la Recherche Médicale (INSERM) Unité 643 Immunointervention dans les Allo et Xenotransplantations, Nantes, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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