|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
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pubmed:dateCreated |
2005-10-12
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|
pubmed:abstractText |
Tenofovir (TDF) is an adenosine nucleotide analogue that has been approved for the treatment of HIV-1 infection. It also shows activity against hepatitis B virus (HBV) in patients with or without lamivudine (LAM)-associated mutations. Development of clinical or virological HBV breakthrough during TDF therapy has not been reported so far. The aim of this study was to analyse the HBV polymerase (pol) from HIV/HBV-coinfected patients with detectable serum levels of HBV DNA during treatment with TDF for longer than 6 months.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1359-6535
|
|
pubmed:author |
pubmed-author:BartholomeuszAngelineA,
pubmed-author:CaminoNuriaN,
pubmed-author:KlausenGerdG,
pubmed-author:KuiperMichaelM,
pubmed-author:LocarniniStephenS,
pubmed-author:LutzThomasT,
pubmed-author:MaussStefanS,
pubmed-author:NúñezMarinaM,
pubmed-author:RodésBertaB,
pubmed-author:SheldonJulieJ,
pubmed-author:SorianoVincentV,
pubmed-author:TackeFrankF
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|
pubmed:issnType |
Print
|
|
pubmed:volume |
10
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
727-34
|
|
pubmed:dateRevised |
2009-11-19
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|
pubmed:meshHeading |
pubmed-meshheading:16218172-Adenine,
pubmed-meshheading:16218172-Adult,
pubmed-meshheading:16218172-Antiviral Agents,
pubmed-meshheading:16218172-DNA, Viral,
pubmed-meshheading:16218172-DNA-Directed DNA Polymerase,
pubmed-meshheading:16218172-Drug Resistance, Viral,
pubmed-meshheading:16218172-HIV Infections,
pubmed-meshheading:16218172-Hepatitis B,
pubmed-meshheading:16218172-Hepatitis B virus,
pubmed-meshheading:16218172-Humans,
pubmed-meshheading:16218172-Models, Molecular,
pubmed-meshheading:16218172-Mutation,
pubmed-meshheading:16218172-Phosphonic Acids,
pubmed-meshheading:16218172-Reverse Transcriptase Inhibitors,
pubmed-meshheading:16218172-Selection, Genetic
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|
pubmed:year |
2005
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|
pubmed:articleTitle |
Selection of hepatitis B virus polymerase mutations in HIV-coinfected patients treated with tenofovir.
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pubmed:affiliation |
Hospital Carlos ill, Madrid, Spain.
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|
pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't
|
