rdf:type |
|
lifeskim:mentions |
umls-concept:C0017262,
umls-concept:C0017337,
umls-concept:C0023861,
umls-concept:C0028828,
umls-concept:C0185117,
umls-concept:C0851285,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1704735,
umls-concept:C1706817,
umls-concept:C2911684,
umls-concept:C2911692
|
pubmed:issue |
2
|
pubmed:dateCreated |
2005-10-31
|
pubmed:abstractText |
An isogenic mutant of Listeria monocytogenes EGD with a deletion of the response regulator gene degU showed a lack of motility due to the absence of flagella. In the present study, we used two-dimensional gel electrophoresis, mass-spectrometry and microarray analyses to identify the listerial genes that depend on DegU for expression. We found that the two L. monocytogenes operons encoding flagella-specific genes and the monocistronically transcribed flaA gene are positively regulated by DegU at 24 degrees C, but are not expressed at 37 degrees C.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Bacterial Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DegU protein, Bacteria,
http://linkedlifedata.com/resource/pubmed/chemical/Flagellin,
http://linkedlifedata.com/resource/pubmed/chemical/Proteome,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Bacterial,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/flaA protein, bacteria
|
pubmed:status |
MEDLINE
|
pubmed:month |
Nov
|
pubmed:issn |
0378-1097
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
252
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
287-98
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16213668-Bacterial Proteins,
pubmed-meshheading:16213668-Electrophoresis, Gel, Two-Dimensional,
pubmed-meshheading:16213668-Flagella,
pubmed-meshheading:16213668-Flagellin,
pubmed-meshheading:16213668-Gene Deletion,
pubmed-meshheading:16213668-Gene Expression Regulation, Bacterial,
pubmed-meshheading:16213668-Listeria monocytogenes,
pubmed-meshheading:16213668-Mass Spectrometry,
pubmed-meshheading:16213668-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16213668-Operon,
pubmed-meshheading:16213668-Proteome,
pubmed-meshheading:16213668-RNA, Bacterial,
pubmed-meshheading:16213668-RNA, Messenger,
pubmed-meshheading:16213668-Temperature
|
pubmed:year |
2005
|
pubmed:articleTitle |
Response regulator DegU of Listeria monocytogenes regulates the expression of flagella-specific genes.
|
pubmed:affiliation |
Lehrstuhl für Mikrobiologie, Theodor Boveri-Institut für Biowissenschaften der Universität Würzburg, Germany.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|