Source:http://linkedlifedata.com/resource/pubmed/id/16213208
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2005-10-10
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pubmed:abstractText |
Despite the importance of the blood-brain barrier (BBB), little is known about the molecular mechanisms that control its integrity. The identification of moody, a gene required for the formation and maintenance of the Drosophila BBB, provides new insight into how paracellular junctions are formed at the barrier. Meanwhile, moody also has been identified in a screen for fly mutants with altered sensitivity to cocaine, remarkably implicating the BBB in the physiological response to narcotics.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0092-8674
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
123
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
9-12
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pubmed:meshHeading |
pubmed-meshheading:16213208-Animals,
pubmed-meshheading:16213208-Blood-Brain Barrier,
pubmed-meshheading:16213208-Cell Adhesion Molecules,
pubmed-meshheading:16213208-Drosophila Proteins,
pubmed-meshheading:16213208-Endothelial Cells,
pubmed-meshheading:16213208-Humans,
pubmed-meshheading:16213208-Neuroglia,
pubmed-meshheading:16213208-Receptors, G-Protein-Coupled,
pubmed-meshheading:16213208-Signal Transduction,
pubmed-meshheading:16213208-Tight Junctions
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pubmed:year |
2005
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pubmed:articleTitle |
The blood-brain barrier--lessons from moody flies.
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pubmed:affiliation |
Department of Neurobiology, Stanford University School of Medicine, CA 94305, USA. rdaneman@stanford.edu
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pubmed:publicationType |
Journal Article,
Review
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