Source:http://linkedlifedata.com/resource/pubmed/id/16209131
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2005-10-7
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pubmed:abstractText |
A new lectin gene was isolated by using genomic walker technology and revealed to encode a mannose-binding lectin. Analysis of a 2233 bp segment revealed a gene including a 1169 bp 5' flanking region, a 417 bp open reading frame (ORF) and a 649 bp 3' flanking region. There are two putative TATA boxes and eight possible CAAT boxes lie in the 5' flanking region. The ORF encodes a 15.1 kDa precursor, which contains a 24-amino acid signal peptide. One possible polyadenylation signal is found in the 3'-flanking region. No intron was detected within the region of genomic sequence corresponding to zaa (Zantedeschia aethiopica agglutinin) full-length cDNA, which is typical of other mannose-binding lectin gene that have been reported. The deduced amino acid sequence of the lectin gene coding region shares 49-54% homology with other known lectins. The cloning of this new lectin gene will allow us to further study its structure, expression and regulation mechanisms.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0144-8463
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
225-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16209131-Amino Acid Sequence,
pubmed-meshheading:16209131-Animals,
pubmed-meshheading:16209131-Base Sequence,
pubmed-meshheading:16209131-Cloning, Molecular,
pubmed-meshheading:16209131-Lectins,
pubmed-meshheading:16209131-Molecular Sequence Data,
pubmed-meshheading:16209131-Open Reading Frames,
pubmed-meshheading:16209131-Plant Proteins,
pubmed-meshheading:16209131-Sequence Alignment,
pubmed-meshheading:16209131-Zantedeschia
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pubmed:year |
2004
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pubmed:articleTitle |
Genomic cloning and characterization of a novel lectin gene from Zantedeschia aethiopica.
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pubmed:affiliation |
State Key Laboratory of Genetic Engineering, School of Life Sciences, Morgan-Tan International Center for Life Sciences, Fudan-SJTU-Nottingham Plant Biotechnology R&D Center, Fudan University, 200433, Shanghai, People's Republic of China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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