rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2005-10-6
|
pubmed:abstractText |
Daptomycin is a new lipopeptide antibiotic that is rapidly bactericidal against Staphylococcus aureus. We report daptomycin resistance and treatment failure in 2 patients with osteomyelitis due to methicillin-resistant S. aureus. Disk diffusion susceptibility testing failed to detect resistance. Daptomycin at high concentration retained bactericidal activity against resistant isolates.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Oct
|
pubmed:issn |
0095-1137
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
43
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
5285-7
|
pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16207998-Aged,
pubmed-meshheading:16207998-Aged, 80 and over,
pubmed-meshheading:16207998-Anti-Bacterial Agents,
pubmed-meshheading:16207998-Bacteremia,
pubmed-meshheading:16207998-Daptomycin,
pubmed-meshheading:16207998-Drug Resistance, Bacterial,
pubmed-meshheading:16207998-Female,
pubmed-meshheading:16207998-Humans,
pubmed-meshheading:16207998-Lumbar Vertebrae,
pubmed-meshheading:16207998-Lumbosacral Region,
pubmed-meshheading:16207998-Methicillin Resistance,
pubmed-meshheading:16207998-Microbial Sensitivity Tests,
pubmed-meshheading:16207998-Middle Aged,
pubmed-meshheading:16207998-Osteomyelitis,
pubmed-meshheading:16207998-Staphylococcal Infections,
pubmed-meshheading:16207998-Staphylococcus aureus,
pubmed-meshheading:16207998-Treatment Failure
|
pubmed:year |
2005
|
pubmed:articleTitle |
Development of Daptomycin resistance in vivo in methicillin-resistant Staphylococcus aureus.
|
pubmed:affiliation |
Rush University Medical Center, Chicago, IL 60612, USA. mhayden@rush.edu
|
pubmed:publicationType |
Journal Article,
Case Reports
|