Linked Life Data

16207502

Source:http://linkedlifedata.com/resource/pubmed/id/16207502

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2006-8-28
pubmed:abstractText
We have initiated a systematic analysis of the role of cholesterol metabolizing genes as risk factors for Alzheimer's disease pathogenesis. As part of this analysis, we have assessed the NR1H2 gene on chromosome 19 and report here a modest association with the locus in sibpairs with late onset disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1558-1497
pubmed:author
pubmed:issnType
Electronic
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1431-4
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed-meshheading:16207502-Aged, pubmed-meshheading:16207502-Aged, 80 and over, pubmed-meshheading:16207502-Alzheimer Disease, pubmed-meshheading:16207502-Apolipoproteins E, pubmed-meshheading:16207502-Chromosome Aberrations, pubmed-meshheading:16207502-Chromosomes, Human, Pair 19, pubmed-meshheading:16207502-DNA Mutational Analysis, pubmed-meshheading:16207502-Female, pubmed-meshheading:16207502-Genetic Predisposition to Disease, pubmed-meshheading:16207502-Genetic Testing, pubmed-meshheading:16207502-Genetic Variation, pubmed-meshheading:16207502-Heterozygote, pubmed-meshheading:16207502-Humans, pubmed-meshheading:16207502-Incidence, pubmed-meshheading:16207502-Male, pubmed-meshheading:16207502-Middle Aged, pubmed-meshheading:16207502-Orphan Nuclear Receptors, pubmed-meshheading:16207502-Polymorphism, Genetic, pubmed-meshheading:16207502-Receptors, Cytoplasmic and Nuclear, pubmed-meshheading:16207502-Retrospective Studies, pubmed-meshheading:16207502-Risk Assessment, pubmed-meshheading:16207502-Risk Factors, pubmed-meshheading:16207502-United States
pubmed:year
2006
pubmed:articleTitle
Genetic variability at the LXR gene (NR1H2) may contribute to the risk of Alzheimer's disease.
pubmed:affiliation
Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Porter Neuroscience Building, 35 Convent Drive, Bethesda, MD 20892 3707, USA.
pubmed:publicationType
Journal Article