Source:http://linkedlifedata.com/resource/pubmed/id/16205437
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
10
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pubmed:dateCreated |
2005-10-5
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pubmed:abstractText |
This is a retrospective case series describing the use of botulinum toxin type A in the treatment of children with congenital muscular torticollis who fail to progress with conservative management. A total of 27 children with congenital muscular torticollis, 6-18 mos of age, received 30 botulinum toxin type A injections into their sternocleidomastoid or upper trapezius muscle, or both, at a pediatric tertiary care center between 1995 and 2001. Three children received repeat injections. Twenty of 27 children (74%) had improved cervical rotation or head tilt after the injections, and 2 of 27 (7%) experienced transient adverse events, specifically, mild dysphagia and neck weakness. This series suggests that botulinum toxin type A may be a safe and effective treatment option for children with congenital muscular torticollis who are unresponsive to a traditional regimen of physical therapy and a home program. A prospective, randomized controlled trial is necessary to definitively assess the role of botulinum toxin type A in this population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0894-9115
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
813-6
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16205437-Botulinum Toxins, Type A,
pubmed-meshheading:16205437-Child, Preschool,
pubmed-meshheading:16205437-Dose-Response Relationship, Drug,
pubmed-meshheading:16205437-Drug Administration Schedule,
pubmed-meshheading:16205437-Female,
pubmed-meshheading:16205437-Follow-Up Studies,
pubmed-meshheading:16205437-Humans,
pubmed-meshheading:16205437-Infant,
pubmed-meshheading:16205437-Injections, Intramuscular,
pubmed-meshheading:16205437-Male,
pubmed-meshheading:16205437-Recovery of Function,
pubmed-meshheading:16205437-Retrospective Studies,
pubmed-meshheading:16205437-Risk Assessment,
pubmed-meshheading:16205437-Severity of Illness Index,
pubmed-meshheading:16205437-Torticollis,
pubmed-meshheading:16205437-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Botulinum toxin type a in the treatment of children with congenital muscular torticollis.
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pubmed:affiliation |
Department of Physical Medicine and Rehabilitation, Children's Hospital, Denver, Colorado 80218, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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