rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2005-12-6
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pubmed:abstractText |
The adipokine adiponectin has insulin-sensitizing, antiatherogenic, and antiinflammatory properties. Mouse and human adiponectin receptor-1 and -2 have been cloned, both of which are expressed in various tissues and mediate effects of globular and full-length adiponectin. Whether adiponectin affects insulin secretion and beta-cell apoptosis and whether plasma adiponectin is associated with beta-cell function in humans is under investigation.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/ADIPOR1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/ADIPOR2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Nonesterified,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Adiponectin,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cell Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Recombinant Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
|
pubmed:issn |
0021-972X
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pubmed:author |
pubmed-author:BrandhorstDD,
pubmed-author:BrendelM DMD,
pubmed-author:BretzelR GRG,
pubmed-author:FritschiMM,
pubmed-author:HäringH-UHU,
pubmed-author:KellererMM,
pubmed-author:MachicaoFF,
pubmed-author:StaigerHH,
pubmed-author:StaigerKK,
pubmed-author:StefanNN,
pubmed-author:StumvollMM
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pubmed:issnType |
Print
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pubmed:volume |
90
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
6707-13
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16204361-Adiponectin,
pubmed-meshheading:16204361-Apoptosis,
pubmed-meshheading:16204361-Fatty Acids, Nonesterified,
pubmed-meshheading:16204361-Female,
pubmed-meshheading:16204361-Humans,
pubmed-meshheading:16204361-Insulin,
pubmed-meshheading:16204361-Insulin-Secreting Cells,
pubmed-meshheading:16204361-Islets of Langerhans,
pubmed-meshheading:16204361-Male,
pubmed-meshheading:16204361-Middle Aged,
pubmed-meshheading:16204361-Receptors, Adiponectin,
pubmed-meshheading:16204361-Receptors, Cell Surface,
pubmed-meshheading:16204361-Recombinant Proteins
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pubmed:year |
2005
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pubmed:articleTitle |
Adiponectin is functionally active in human islets but does not affect insulin secretory function or beta-cell lipoapoptosis.
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pubmed:affiliation |
Department of Internal Medicine, University of Tübingen, Otfried-Müller Strasse 10, 72076 Tübingen, Germany.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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