Linked Life Data

16203772

Source:http://linkedlifedata.com/resource/pubmed/id/16203772

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19 Pt 1
pubmed:dateCreated
2005-10-5
pubmed:abstractText
The Arg/Pro polymorphism in codon 72 of p53 was recently associated with age of onset of colorectal cancer in Lynch syndrome. A novel polymorphism in the promoter region of MDM2 was associated with age of cancer onset in Li-Fraumeni syndrome. We studied the influence of both polymorphisms on age of onset in Lynch syndrome and of the p53 polymorphism also in sporadic colorectal cancer.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
1078-0432
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6840-4
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:16203772-Adult, pubmed-meshheading:16203772-Age of Onset, pubmed-meshheading:16203772-Aged, pubmed-meshheading:16203772-Aged, 80 and over, pubmed-meshheading:16203772-Alleles, pubmed-meshheading:16203772-Case-Control Studies, pubmed-meshheading:16203772-Codon, pubmed-meshheading:16203772-Colorectal Neoplasms, pubmed-meshheading:16203772-Colorectal Neoplasms, Hereditary Nonpolyposis, pubmed-meshheading:16203772-Female, pubmed-meshheading:16203772-Finland, pubmed-meshheading:16203772-Gene Frequency, pubmed-meshheading:16203772-Genes, p53, pubmed-meshheading:16203772-Genetic Variation, pubmed-meshheading:16203772-Genotype, pubmed-meshheading:16203772-Humans, pubmed-meshheading:16203772-Male, pubmed-meshheading:16203772-Microsatellite Repeats, pubmed-meshheading:16203772-Middle Aged, pubmed-meshheading:16203772-Models, Statistical, pubmed-meshheading:16203772-Polymorphism, Genetic, pubmed-meshheading:16203772-Proportional Hazards Models, pubmed-meshheading:16203772-Proto-Oncogene Proteins c-mdm2, pubmed-meshheading:16203772-Risk, pubmed-meshheading:16203772-Tumor Suppressor Protein p53
pubmed:year
2005
pubmed:articleTitle
p53 codon 72 and MDM2 SNP309 polymorphisms and age of colorectal cancer onset in Lynch syndrome.
pubmed:affiliation
Human Cancer Genetics Program, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio 43210, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural