Source:http://linkedlifedata.com/resource/pubmed/id/16198831
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-10-3
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pubmed:abstractText |
Dairy cream, as a suspension of lipid droplets in water, is a potentially useful magnetic resonance imaging (MRI) phantom material and an interesting material for studying fundamental relaxation mechanisms. Here we report a strong increase in the transverse relaxation rates with field strength for both the water and lipid protons in dairy cream. Also, studies at 4.7 T reveal a nonlinear response of transverse relaxation rates with increasing concentration of a common gadolinium (Gd)-based contrast agent, including an initial decrease of water relaxation rates as measured with Hahn spin echoes at the lower Gd concentrations. The results are treated within the framework of a model in which the magnetic susceptibility difference between the lipid droplets and the aqueous phase plays the prominent role for transverse relaxation. Second-order polynomial fits of the water proton transverse relaxation rate dependence on field strength and on Gd concentration at 4.7 T provided experimental parameters from which model parameters are extracted and compared with expectations available from the literature.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Contrast Media,
http://linkedlifedata.com/resource/pubmed/chemical/Gadolinium,
http://linkedlifedata.com/resource/pubmed/chemical/Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Protons,
http://linkedlifedata.com/resource/pubmed/chemical/Water
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0730-725X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
757-64
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16198831-Contrast Media,
pubmed-meshheading:16198831-Dairy Products,
pubmed-meshheading:16198831-Gadolinium,
pubmed-meshheading:16198831-Lipids,
pubmed-meshheading:16198831-Magnetic Resonance Imaging,
pubmed-meshheading:16198831-Nonlinear Dynamics,
pubmed-meshheading:16198831-Phantoms, Imaging,
pubmed-meshheading:16198831-Protons,
pubmed-meshheading:16198831-Water
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pubmed:year |
2005
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pubmed:articleTitle |
On the strong field dependence and nonlinear response to gadolinium contrast agent of proton transverse relaxation rates in dairy cream.
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pubmed:affiliation |
Department of Radiology, Children's Hospital, Boston, MA 02468, USA. rmulkern@yahoo.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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