16198252

Source:http://linkedlifedata.com/resource/pubmed/id/16198252

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0034693, umls-concept:C0205191, umls-concept:C0205263, umls-concept:C0205464, umls-concept:C0449468, umls-concept:C0600520, umls-concept:C1292733, umls-concept:C2248477
pubmed:issue	7
pubmed:dateCreated	2005-10-3
pubmed:abstractText	Left ventricular (LV) hypertrophy and dilation are important compensatory responses to chronic volume overload; however, the mechanisms responsible for this LV remodeling have not been well characterized. Previous observations that the number of myocardial mast cells are increased in congestive heart failure (CHF) suggested the hypothesis that mast cells might be involved in the ventricular remodeling induced by a chronic volume overload.
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/R01-HL073990, http://linkedlifedata.com/resource/pubmed/grant/R01-HL62228
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9442138
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Anti-Inflammatory Agents, http://linkedlifedata.com/resource/pubmed/chemical/Nedocromil
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	1071-9164
pubmed:author	pubmed-author:BrowerGregory LGL, pubmed-author:JanickiJoseph SJS
pubmed:issnType	Print
pubmed:volume	11
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	548-56
pubmed:dateRevised	2007-11-15
pubmed:meshHeading	pubmed-meshheading:16198252-Animals, pubmed-meshheading:16198252-Anti-Inflammatory Agents, pubmed-meshheading:16198252-Cell Degranulation, pubmed-meshheading:16198252-Chronic Disease, pubmed-meshheading:16198252-Disease Models, Animal, pubmed-meshheading:16198252-Dose-Response Relationship, Drug, pubmed-meshheading:16198252-Heart Failure, pubmed-meshheading:16198252-Heart Ventricles, pubmed-meshheading:16198252-Hypertrophy, Left Ventricular, pubmed-meshheading:16198252-Male, pubmed-meshheading:16198252-Mast Cells, pubmed-meshheading:16198252-Myocardial Contraction, pubmed-meshheading:16198252-Nedocromil, pubmed-meshheading:16198252-Organ Size, pubmed-meshheading:16198252-Rats, pubmed-meshheading:16198252-Rats, Sprague-Dawley, pubmed-meshheading:16198252-Stroke Volume, pubmed-meshheading:16198252-Vasodilation, pubmed-meshheading:16198252-Ventricular Function, Left, pubmed-meshheading:16198252-Ventricular Pressure, pubmed-meshheading:16198252-Ventricular Remodeling
pubmed:year	2005
pubmed:articleTitle	Pharmacologic inhibition of mast cell degranulation prevents left ventricular remodeling induced by chronic volume overload in rats.
pubmed:affiliation	Department of Anatomy, Physiology and Pharmacology, Auburn University, Auburn, Alabama, USA.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S., Research Support, U.S. Gov't, Non-P.H.S., Research Support, N.I.H., Extramural