Linked Life Data

16194079

Source:http://linkedlifedata.com/resource/pubmed/id/16194079

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
19
pubmed:dateCreated
2005-9-30
pubmed:abstractText
We report a novel enzyme-based microcantilever sensor by using layer-by-layer nanoassembly modification. A glucose oxidase (GOx) functionalized microcantilever underwent bending when it was exposed to glucose solutions. The magnitudes of bending were proportional to the concentrations of glucose. The cantilever bending was specific toward glucose, but not to other sugars such as mannose, fructose, or galactose. The flow rate effect on the cantilever bending response is also discussed. The bending mechanism was investigated, and the kinetic and thermodynamic analysis and experimental results showed that the conformational change of GOx and gluconic formation were the origin of cantilever deflection.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0003-2700
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
6197-204
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Glucose oxidase multilayer modified microcantilevers for glucose measurement.
pubmed:affiliation
Department of Chemistry, Institute for Micromanufacturing, Louisiana Tech University, Ruston, Louisiana 71272, USA.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, Non-P.H.S.