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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
12
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pubmed:dateCreated |
2005-12-6
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pubmed:abstractText |
The new antibody pertuzumab (Omnitarg) targets the dimerisation subdomain of HER-2. The purpose of this study was to analyse whether pertuzumab retains HER-2 targeting capacity after labelling with the therapeutically interesting beta emitter (177)Lu and to make initial characterizations in vitro and in vivo.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized,
http://linkedlifedata.com/resource/pubmed/chemical/Lutetium,
http://linkedlifedata.com/resource/pubmed/chemical/Radioisotopes,
http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals,
http://linkedlifedata.com/resource/pubmed/chemical/Receptor, erbB-2,
http://linkedlifedata.com/resource/pubmed/chemical/pertuzumab
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
1619-7070
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
32
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1457-62
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16193312-Animals,
pubmed-meshheading:16193312-Antibodies, Monoclonal,
pubmed-meshheading:16193312-Antibodies, Monoclonal, Humanized,
pubmed-meshheading:16193312-Cell Line, Tumor,
pubmed-meshheading:16193312-Drug Delivery Systems,
pubmed-meshheading:16193312-Female,
pubmed-meshheading:16193312-Humans,
pubmed-meshheading:16193312-Lutetium,
pubmed-meshheading:16193312-Metabolic Clearance Rate,
pubmed-meshheading:16193312-Mice,
pubmed-meshheading:16193312-Mice, Inbred BALB C,
pubmed-meshheading:16193312-Organ Specificity,
pubmed-meshheading:16193312-Ovarian Neoplasms,
pubmed-meshheading:16193312-Radioimmunotherapy,
pubmed-meshheading:16193312-Radioisotopes,
pubmed-meshheading:16193312-Radiopharmaceuticals,
pubmed-meshheading:16193312-Receptor, erbB-2,
pubmed-meshheading:16193312-Staining and Labeling,
pubmed-meshheading:16193312-Tissue Distribution
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pubmed:year |
2005
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pubmed:articleTitle |
[(177)Lu]pertuzumab: experimental studies on targeting of HER-2 positive tumour cells.
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pubmed:affiliation |
Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden. mikael.persson@bms.uu.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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