Most of the world's children live in regions where laboratory facilities are not available. In these regions, clinical prediction rules can be useful to guide clinicians' decisions on antibiotic therapy for streptococcal pharyngitis, and to reduce routine presumptive antibiotic therapy for all pharyngitis.
Department of International Health, Bloomberg School of Public Health, Department of Pediatrics, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA. msteinho@jhsph.edu