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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
2005-9-27
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pubmed:abstractText |
Fibrovascular tissue formation in diabetic retinopathy necessitates not only angiogenic activity but also proteolytic activity, which is at least in part attributable to the induction of membrane-type 1 matrix metalloproteinase (MT1-MMP) in retinal glial cells. However, little is known about the triggers for MT1-MMP induction in the diabetic retina. In the present study, the effect of tissue hypoxia on MT1-MMP expression in retinal glial cells was investigated.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0146-0404
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
46
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
3817-24
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:16186369-Animals,
pubmed-meshheading:16186369-Anoxia,
pubmed-meshheading:16186369-Blotting, Western,
pubmed-meshheading:16186369-Cells, Cultured,
pubmed-meshheading:16186369-Cinnamates,
pubmed-meshheading:16186369-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16186369-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:16186369-Matrix Metalloproteinases, Membrane-Associated,
pubmed-meshheading:16186369-Metalloendopeptidases,
pubmed-meshheading:16186369-Neuroglia,
pubmed-meshheading:16186369-RNA, Messenger,
pubmed-meshheading:16186369-Rabbits,
pubmed-meshheading:16186369-Retina,
pubmed-meshheading:16186369-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16186369-Vascular Endothelial Growth Factor A,
pubmed-meshheading:16186369-Vascular Endothelial Growth Factor Receptor-1,
pubmed-meshheading:16186369-Vascular Endothelial Growth Factor Receptor-2
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pubmed:year |
2005
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pubmed:articleTitle |
Hypoxia induces the expression of membrane-type 1 matrix metalloproteinase in retinal glial cells.
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pubmed:affiliation |
Department of Pathology, Keio University School of Medicine, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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