Linked Life Data

16185927

Source:http://linkedlifedata.com/resource/pubmed/id/16185927

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2005-11-21
pubmed:abstractText
Immunoreceptor signalling leads to Ca2+ release from intracellular stores, which is followed by the entry of external Ca2+ into the cell through mysterious store-operated Ca2+ (SOC) channels. Recent studies have identified stromal interaction molecules (STIMs) as having an essential role in SOC influx. Remarkably, Ca2+ store depletion induces a rapid redistribution of the endoplasmic reticulum STIM1 into puncta that accumulate near the plasma membrane. The combined data suggest that STIM1 functions as a Ca2+ sensor in the signalling pathways connecting Ca2+ store depletion to SOC entry.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1471-4906
pubmed:author
pubmed:issnType
Print
pubmed:volume
26
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
621-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Lifting the fog in store-operated Ca2+ entry.
pubmed:affiliation
Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Videnská 1083, 142 20 Prague 4, Czech Republic. draberpe@biomed.cas.cz
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't