|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
15
|
|
pubmed:dateCreated |
2005-9-26
|
|
pubmed:abstractText |
Although highly active antiretroviral therapy has significantly reduced morbidity and mortality in HIV-infected children, it often fails to completely suppress viral replication, thereby allowing the emergence of drug-resistant variants. Protease inhibitor (PI) based therapy has been hypothesized to depress cell-mediated immune responses by reducing antigen presentation.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0269-9370
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
14
|
|
pubmed:volume |
19
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1575-85
|
|
pubmed:dateRevised |
2008-11-21
|
|
pubmed:meshHeading |
pubmed-meshheading:16184026-Adolescent,
pubmed-meshheading:16184026-Antiretroviral Therapy, Highly Active,
pubmed-meshheading:16184026-CD4 Lymphocyte Count,
pubmed-meshheading:16184026-CD4-Positive T-Lymphocytes,
pubmed-meshheading:16184026-CD8-Positive T-Lymphocytes,
pubmed-meshheading:16184026-Child,
pubmed-meshheading:16184026-Child, Preschool,
pubmed-meshheading:16184026-Cytokines,
pubmed-meshheading:16184026-Drug Administration Schedule,
pubmed-meshheading:16184026-Flow Cytometry,
pubmed-meshheading:16184026-HIV Infections,
pubmed-meshheading:16184026-HIV Protease Inhibitors,
pubmed-meshheading:16184026-HIV-1,
pubmed-meshheading:16184026-Humans,
pubmed-meshheading:16184026-Immunity, Cellular,
pubmed-meshheading:16184026-Immunophenotyping,
pubmed-meshheading:16184026-Infectious Disease Transmission, Vertical,
pubmed-meshheading:16184026-Lymphocyte Activation,
pubmed-meshheading:16184026-Retrospective Studies,
pubmed-meshheading:16184026-Viral Load
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Partial treatment interruption of protease inhibitors augments HIV-specific immune responses in vertically infected pediatric patients.
|
|
pubmed:affiliation |
Gladstone Institute of Virology and Immunology, University of California, San Francisco, California 94158-2261, USA. flegrand@gladstone.ucsf.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
