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pubmed-article:16183563pubmed:abstractTextLevels of the proinflammatory cytokine interleukin 6 (IL-6) increase after surgery. The functional polymorphism in the IL-6 promoter region, G-174C, is associated with an increased risk of coronary heart disease. We investigated the genetic predisposition in IL-6 response to coronary revascularization and studied the association between the G-174C polymorphism, IL-6 levels, and clinical outcomes of surgery.lld:pubmed
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pubmed-article:16183563pubmed:articleTitleInterleukin 6 G-174C polymorphism influences outcome following coronary revascularization surgery.lld:pubmed
pubmed-article:16183563pubmed:affiliationDepartment of Cardiothoracic Surgery, South Manchester University Hospitals NHS Trust, Manchester, UK. mbittar@doctors.org.uklld:pubmed
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