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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1992-8-6
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pubmed:abstractText |
The release of endothelin-1 from mesenteric arteries from cyclosporine-treated rats was measured by a specific enzyme immunoassay after purification of the perfusate on an immunoaffinity column. Mesenteric arteries from cyclosporine-treated rats (25 mg/kg per day for 6 weeks) released a significantly larger amount of endothelin-1 than arteries from vehicle-treated control rats (P less than 0.05). Serum creatinine levels were not significantly different in the two groups. These findings indicate that cyclosporine is a potential inducer of endothelin release from the mesenteric artery.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0014-2999
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
31
|
pubmed:volume |
213
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
445-7
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1618283-Animals,
pubmed-meshheading:1618283-Blood Pressure,
pubmed-meshheading:1618283-Cyclosporine,
pubmed-meshheading:1618283-Endothelins,
pubmed-meshheading:1618283-Hypertension,
pubmed-meshheading:1618283-Male,
pubmed-meshheading:1618283-Mesenteric Arteries,
pubmed-meshheading:1618283-Rats,
pubmed-meshheading:1618283-Rats, Inbred Strains
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pubmed:year |
1992
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pubmed:articleTitle |
Endothelin-1 release from the mesenteric arteries of cyclosporine-treated rats.
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pubmed:affiliation |
Second Department of Internal Medicine, School of Medicine, Kanazawa University, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study
|