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rdf:type |
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|
lifeskim:mentions |
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pubmed:issue |
1-2
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pubmed:dateCreated |
2006-2-6
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|
pubmed:abstractText |
Isoniazid (INH) is widely used in the therapy of tuberculosis. Poor metabolizer (PM) of the NAT2 is an important reason of inter-individual difference of the plasma INH concentration. We studied the relationship between NAT2 genotype and INH and its metabolite acetylisoniazid (AcINH) concentration in Chinese people.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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|
pubmed:month |
Mar
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|
pubmed:issn |
0009-8981
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
365
|
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
104-8
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pubmed:dateRevised |
2010-9-8
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pubmed:meshHeading |
pubmed-meshheading:16182272-Antitubercular Agents,
pubmed-meshheading:16182272-Arylamine N-Acetyltransferase,
pubmed-meshheading:16182272-China,
pubmed-meshheading:16182272-Chromatography, High Pressure Liquid,
pubmed-meshheading:16182272-Genotype,
pubmed-meshheading:16182272-Heterozygote,
pubmed-meshheading:16182272-Homozygote,
pubmed-meshheading:16182272-Humans,
pubmed-meshheading:16182272-Isoniazid,
pubmed-meshheading:16182272-Tuberculosis, Pulmonary
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|
pubmed:year |
2006
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|
pubmed:articleTitle |
The influence of NAT2 genotypes on the plasma concentration of isoniazid and acetylisoniazid in Chinese pulmonary tuberculosis patients.
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|
pubmed:affiliation |
Department of Clinical Pharmacology, Jinling Hospital, 305 East Zhongshan Road, Nanjing 210002, PR China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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