Source:http://linkedlifedata.com/resource/pubmed/id/16182268
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1-2
|
| pubmed:dateCreated |
2005-12-6
|
| pubmed:abstractText |
Real-time (RT) PCR methods for discovering and genotyping single nucleotide polymorphisms (SNPs) are becoming increasingly important in various fields of biological sciences. SNP genotyping is widely used to perform genetic association studies aimed at characterising the genetic factors underlying inherited traits. The detection and quantification of somatic mutations is an important tool for investigating the genetic causes of tumorigenesis. In infectious disease diagnostics there is an increasing emphasis placed on genotyping variation within the genomes of pathogenic organisms in order to distinguish between strains.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jan
|
| pubmed:issn |
0009-8981
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
363
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
32-47
|
| pubmed:dateRevised |
2006-11-15
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| pubmed:meshHeading |
pubmed-meshheading:16182268-Animals,
pubmed-meshheading:16182268-DNA Mutational Analysis,
pubmed-meshheading:16182268-Genotype,
pubmed-meshheading:16182268-Humans,
pubmed-meshheading:16182268-Mutation,
pubmed-meshheading:16182268-Polymerase Chain Reaction,
pubmed-meshheading:16182268-Polymorphism, Single Nucleotide,
pubmed-meshheading:16182268-Reproducibility of Results,
pubmed-meshheading:16182268-Sequence Analysis, DNA
|
| pubmed:year |
2006
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| pubmed:articleTitle |
The use of real-time PCR methods in DNA sequence variation analysis.
|
| pubmed:affiliation |
R&D Genetics, AstraZeneca Pharmaceuticals, 19G9 Mereside, Macclesfield, Cheshire, UK. neil.gibson@astrazeneca.com
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| pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't
|