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rdf:type |
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lifeskim:mentions |
umls-concept:C0007600,
umls-concept:C0020223,
umls-concept:C0025723,
umls-concept:C0034804,
umls-concept:C0035820,
umls-concept:C0056912,
umls-concept:C0449438,
umls-concept:C0598864,
umls-concept:C1512505,
umls-concept:C1537647,
umls-concept:C2603343
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|
pubmed:issue |
5
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pubmed:dateCreated |
2005-9-26
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pubmed:abstractText |
To detect the 5'CpG island methylation of estrogen receptor (ER) alpha gene promotor region in ER alpha-negative human breast cancer cell lines (MDA-MB-231 and MDA-MB-435) and breast cancer tissues; and to investigate the possibility of hydralazine in restoring the expression of ER alpha gene through demethylation.
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pubmed:language |
chi
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0529-5807
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
283-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16181550-Adult,
pubmed-meshheading:16181550-Aged,
pubmed-meshheading:16181550-Breast Neoplasms,
pubmed-meshheading:16181550-Carcinoma, Ductal, Breast,
pubmed-meshheading:16181550-Cell Line, Tumor,
pubmed-meshheading:16181550-CpG Islands,
pubmed-meshheading:16181550-DNA Methylation,
pubmed-meshheading:16181550-Estrogen Receptor alpha,
pubmed-meshheading:16181550-Female,
pubmed-meshheading:16181550-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16181550-Gene Silencing,
pubmed-meshheading:16181550-Humans,
pubmed-meshheading:16181550-Hydralazine,
pubmed-meshheading:16181550-Middle Aged,
pubmed-meshheading:16181550-Promoter Regions, Genetic,
pubmed-meshheading:16181550-RNA, Messenger
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pubmed:year |
2005
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pubmed:articleTitle |
[Study of the CpG methylation status of ER alpha gene in estrogen receptor alpha-negative breast cancer cell lines and the role of hydralazine demethylation].
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pubmed:affiliation |
Breast Center, Southwest Hospital, Chongqing 400038, China.
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pubmed:publicationType |
Journal Article,
English Abstract
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