|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
12
|
|
pubmed:dateCreated |
2005-12-6
|
|
pubmed:abstractText |
Hypospadias is one of the most common malformations in man, with an incidence of 1:300 in newborn boys. No gene has been identified that causes isolated hypospadias, but the androgenic influence is important during male genital development.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0021-972X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
90
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
6695-8
|
|
pubmed:dateRevised |
2010-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:16174723-3-Oxo-5-alpha-Steroid 4-Dehydrogenase,
pubmed-meshheading:16174723-Alleles,
pubmed-meshheading:16174723-Base Sequence,
pubmed-meshheading:16174723-Case-Control Studies,
pubmed-meshheading:16174723-DNA,
pubmed-meshheading:16174723-Gene Frequency,
pubmed-meshheading:16174723-Genetic Predisposition to Disease,
pubmed-meshheading:16174723-Heterozygote,
pubmed-meshheading:16174723-Homozygote,
pubmed-meshheading:16174723-Humans,
pubmed-meshheading:16174723-Hypospadias,
pubmed-meshheading:16174723-Infant, Newborn,
pubmed-meshheading:16174723-Leucine,
pubmed-meshheading:16174723-Male,
pubmed-meshheading:16174723-Molecular Sequence Data,
pubmed-meshheading:16174723-Polymorphism, Genetic,
pubmed-meshheading:16174723-Valine
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
The valine allele of the V89L polymorphism in the 5-alpha-reductase gene confers a reduced risk for hypospadias.
|
|
pubmed:affiliation |
Department of Molecular Medicine, Karolinska Institutet, Stockholm, Sweden.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
