16170642

Source:http://linkedlifedata.com/resource/pubmed/id/16170642

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0017480, umls-concept:C0018023, umls-concept:C0030705, umls-concept:C0034656, umls-concept:C0035171, umls-concept:C1274040, umls-concept:C2603343
pubmed:issue	9
pubmed:dateCreated	2005-9-19
pubmed:abstractText	Although levothyroxine is the mostly prescribed medicament in Germany, its therapeutic effectiveness in nodular goiter was never studied in a randomized, double-blind trial with sufficient power. Thus, in May 2004 a TSH-adapted (TSH: thyroid-stimulating hormone), randomized, doubleblind, placebo-controlled four-arm (placebo [P] vs. levothyroxine [T] vs. iodine [I] vs. levothyroxine + iodine [TI]) multicenter study was started in Germany (LISA study).
pubmed:language	ger
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8303501
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Iodides, http://linkedlifedata.com/resource/pubmed/chemical/Iodine, http://linkedlifedata.com/resource/pubmed/chemical/Placebos, http://linkedlifedata.com/resource/pubmed/chemical/Thyrotropin, http://linkedlifedata.com/resource/pubmed/chemical/Thyroxine
pubmed:status	MEDLINE
pubmed:month	Sep
pubmed:issn	0723-5003
pubmed:author	pubmed-author:GrussendorfMartinM, pubmed-author:LISA-Studiengruppe, pubmed-author:ReinersChristophC, pubmed-author:VaupelRenateR, pubmed-author:WegscheiderKarlK
pubmed:issnType	Print
pubmed:day	15
pubmed:volume	100
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	542-6
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:16170642-Adolescent, pubmed-meshheading:16170642-Adult, pubmed-meshheading:16170642-Data Interpretation, Statistical, pubmed-meshheading:16170642-Double-Blind Method, pubmed-meshheading:16170642-Drug Therapy, Combination, pubmed-meshheading:16170642-Female, pubmed-meshheading:16170642-Goiter, Nodular, pubmed-meshheading:16170642-Humans, pubmed-meshheading:16170642-Iodides, pubmed-meshheading:16170642-Iodine, pubmed-meshheading:16170642-Male, pubmed-meshheading:16170642-Middle Aged, pubmed-meshheading:16170642-Patient Compliance, pubmed-meshheading:16170642-Placebos, pubmed-meshheading:16170642-Prospective Studies, pubmed-meshheading:16170642-Quality Control, pubmed-meshheading:16170642-Thyrotropin, pubmed-meshheading:16170642-Thyroxine, pubmed-meshheading:16170642-Time Factors
pubmed:year	2005
pubmed:articleTitle	[The LISA trial-a- randomized, double-blind, placebo-controlled four-arm study of 1,000 patients with nodular goiter in Germany. Study Design and first results of feasibility].
pubmed:affiliation	Endokrinologie und Diabetologie im Zentrum, Stuttgart. martin@grussendorf.de
pubmed:publicationType	Journal Article, Clinical Trial, Comparative Study, English Abstract, Randomized Controlled Trial, Multicenter Study