Source:http://linkedlifedata.com/resource/pubmed/id/16169366
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2005-9-19
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pubmed:abstractText |
This study analyzed the effect of beta-blocker therapy at discharge on 1-year mortality rate in a large, unselected cohort of patients who had ST-segment elevation myocardial infarction that was treated by primary angioplasty. Our population is represented by 1,513 patients. At 1-year follow-up, beta blockers at discharge were associated with a significant decrease in mortality rate (2.9% vs 8.5%, RR 0.33, 95% confidence interval [CI] 0.18 to 0.59, p <0.0001), particularly in patients who had anterior wall infarction (3.9% vs 13.4%, RR 0.28, 95% CI 0.14 to 0.54, p <0.0001), whereas nonsignificant benefits were observed in patients who had nonanterior wall infarction (2.0% vs 3.3%, RR 0.6, 95% CI 0.17 to 2.07, p = NS). Benefits in terms of mortality rate that were conferred by beta blockers were confirmed at multivariate analysis that was restricted to patients who had anterior wall infarction (RR 0.43, 95% CI 0.21 to 0.86, p = 0.022).
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0002-9149
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
96
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
806-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16169366-Adrenergic beta-Antagonists,
pubmed-meshheading:16169366-Aged,
pubmed-meshheading:16169366-Angioplasty, Balloon, Coronary,
pubmed-meshheading:16169366-Electrocardiography,
pubmed-meshheading:16169366-Female,
pubmed-meshheading:16169366-Follow-Up Studies,
pubmed-meshheading:16169366-Heart Conduction System,
pubmed-meshheading:16169366-Humans,
pubmed-meshheading:16169366-Male,
pubmed-meshheading:16169366-Middle Aged,
pubmed-meshheading:16169366-Multivariate Analysis,
pubmed-meshheading:16169366-Myocardial Infarction,
pubmed-meshheading:16169366-Patient Discharge,
pubmed-meshheading:16169366-Time Factors,
pubmed-meshheading:16169366-Treatment Outcome
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pubmed:year |
2005
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pubmed:articleTitle |
Impact of beta-blocker therapy at discharge on long-term mortality after primary angioplasty for ST-segment elevation myocardial infarction.
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pubmed:affiliation |
The Division of Cardiology, ISALA Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands.
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pubmed:publicationType |
Journal Article
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