Source:http://linkedlifedata.com/resource/pubmed/id/16168642
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
22
|
| pubmed:dateCreated |
2005-10-5
|
| pubmed:abstractText |
The first carbohydrate-free aminoglycoside analogs bearing the 2-deoxystreptamine moiety were synthesized from asymmetrically protected 2-deoxystrepamine and subsequently demonstrated to have significant binding to the 16S A-site rRNA target and moderate functional activity.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0960-894X
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
15
|
| pubmed:volume |
15
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
4919-22
|
| pubmed:meshHeading |
pubmed-meshheading:16168642-Aminoglycosides,
pubmed-meshheading:16168642-Inhibitory Concentration 50,
pubmed-meshheading:16168642-Molecular Structure,
pubmed-meshheading:16168642-Protein Biosynthesis,
pubmed-meshheading:16168642-RNA, Ribosomal, 16S,
pubmed-meshheading:16168642-Transcription, Genetic
|
| pubmed:year |
2005
|
| pubmed:articleTitle |
The synthesis and 16S A-site rRNA recognition of carbohydrate-free aminoglycosides.
|
| pubmed:affiliation |
Ibis Therapeutics, A Division of Isis Pharmaceuticals, Inc., 2292 Faraday Avenue, Carlsbad, CA 92008, USA.
|
| pubmed:publicationType |
Journal Article
|