Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
2005-9-16
pubmed:abstractText
The conventional therapy for locally advanced rectal cancer involves surgery and adjuvant therapy. The standard adjuvant therapy is combined modality treatment, including 5-fluorouracil chemotherapy and radiation. The standard of care in terms of timing of adjuvant therapy, whether pre- or postoperative, continues to evolve, and potential advantages and disadvantages exist for both neoadjuvant and adjuvant combined modality therapy. Newer modalities of assessment, such as endoscopic ultrasound, have had an impact on more accurate staging of locally advanced rectal cancer, thus impacting the choice of therapy. Continued emphasis on improving survival, decreasing local recurrence, and minimizing treatment toxicity to improve quality of life are the goals of ongoing research in the field of rectal cancer.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1543-0790
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
806-14
pubmed:dateRevised
2005-11-16
pubmed:meshHeading
pubmed:year
2004
pubmed:articleTitle
Pre- and postoperative adjuvant therapy for locally advanced rectal cancer.
pubmed:affiliation
Department of Medicine, Division of Hematology and Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
pubmed:publicationType
Journal Article, Review