|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0012854,
umls-concept:C0023467,
umls-concept:C0030705,
umls-concept:C1334913,
umls-concept:C1336658,
umls-concept:C1336767,
umls-concept:C1413246,
umls-concept:C1708111,
umls-concept:C1709390,
umls-concept:C1826471,
umls-concept:C1837441
|
|
pubmed:issue |
18
|
|
pubmed:dateCreated |
2005-9-16
|
|
pubmed:abstractText |
The nucleoporin 98 kDa (NUP98) gene has been reported to be fused to 17 different partner genes in various hematologic malignancies with 11p15 aberrations. Cytogenetic analysis of an adult de novo acute myelogenous leukemia (M5a) revealed a t(3;11)(p24;p15), suggesting rearrangement of NUP98 with a novel partner gene.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/DNA Topoisomerases, Type II,
http://linkedlifedata.com/resource/pubmed/chemical/DNA topoisomerase II beta,
http://linkedlifedata.com/resource/pubmed/chemical/DNA-Binding Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nuclear Pore Complex Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nup98 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Oncogene Proteins, Fusion,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Neoplasm
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Sep
|
|
pubmed:issn |
1078-0432
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
6489-94
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16166424-Acute Disease,
pubmed-meshheading:16166424-Amino Acid Sequence,
pubmed-meshheading:16166424-Base Sequence,
pubmed-meshheading:16166424-Chromosomes, Human, Pair 11,
pubmed-meshheading:16166424-Chromosomes, Human, Pair 3,
pubmed-meshheading:16166424-DNA Topoisomerases, Type II,
pubmed-meshheading:16166424-DNA-Binding Proteins,
pubmed-meshheading:16166424-Humans,
pubmed-meshheading:16166424-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16166424-Leukemia, Myeloid,
pubmed-meshheading:16166424-Male,
pubmed-meshheading:16166424-Middle Aged,
pubmed-meshheading:16166424-Molecular Sequence Data,
pubmed-meshheading:16166424-Nuclear Pore Complex Proteins,
pubmed-meshheading:16166424-Oncogene Proteins, Fusion,
pubmed-meshheading:16166424-RNA, Neoplasm,
pubmed-meshheading:16166424-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16166424-Sequence Homology, Nucleic Acid,
pubmed-meshheading:16166424-Translocation, Genetic
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
NUP98 is fused to topoisomerase (DNA) IIbeta 180 kDa (TOP2B) in a patient with acute myeloid leukemia with a new t(3;11)(p24;p15).
|
|
pubmed:affiliation |
Children's Cancer Research Institute, Vienna, Austria.
|
|
pubmed:publicationType |
Journal Article,
Case Reports,
Research Support, Non-U.S. Gov't
|
