|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
4
|
|
pubmed:dateCreated |
2005-9-16
|
|
pubmed:abstractText |
The activity of the organic anion transporter 1 (OAT1) has been implicated recently in the basolateral uptake of thiol conjugates of inorganic mercury in renal proximal tubular cells. However, very little is known about the role of OAT1 in the renal epithelial transport of organic forms of mercury, such as methylmercury (CH(3)Hg(+)), especially when it is in the form of the cysteine (Cys) S-conjugate of methylmercury (CH(3)Hg-Cys), which is believed to be a biologically relevant form of mercury.
|
|
pubmed:grant |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Cysteine,
http://linkedlifedata.com/resource/pubmed/chemical/Dicarboxylic Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Glutarates,
http://linkedlifedata.com/resource/pubmed/chemical/Leucine,
http://linkedlifedata.com/resource/pubmed/chemical/Methylmercury Compounds,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transport Protein 1,
http://linkedlifedata.com/resource/pubmed/chemical/Probenecid,
http://linkedlifedata.com/resource/pubmed/chemical/Tritium,
http://linkedlifedata.com/resource/pubmed/chemical/Uricosuric Agents,
http://linkedlifedata.com/resource/pubmed/chemical/methylmercury cysteine,
http://linkedlifedata.com/resource/pubmed/chemical/p-Aminohippuric Acid
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Oct
|
|
pubmed:issn |
0085-2538
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
68
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1684-99
|
|
pubmed:dateRevised |
2007-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:16164645-Animals,
pubmed-meshheading:16164645-Biological Transport,
pubmed-meshheading:16164645-Cell Line,
pubmed-meshheading:16164645-Cell Survival,
pubmed-meshheading:16164645-Cysteine,
pubmed-meshheading:16164645-Dicarboxylic Acids,
pubmed-meshheading:16164645-Dogs,
pubmed-meshheading:16164645-Dose-Response Relationship, Drug,
pubmed-meshheading:16164645-Epithelial Cells,
pubmed-meshheading:16164645-Glutarates,
pubmed-meshheading:16164645-Humans,
pubmed-meshheading:16164645-Kidney,
pubmed-meshheading:16164645-Leucine,
pubmed-meshheading:16164645-Methylmercury Compounds,
pubmed-meshheading:16164645-Organic Anion Transport Protein 1,
pubmed-meshheading:16164645-Probenecid,
pubmed-meshheading:16164645-Temperature,
pubmed-meshheading:16164645-Transfection,
pubmed-meshheading:16164645-Tritium,
pubmed-meshheading:16164645-Uricosuric Agents,
pubmed-meshheading:16164645-p-Aminohippuric Acid
|
|
pubmed:year |
2005
|
|
pubmed:articleTitle |
Handling of cysteine S-conjugates of methylmercury in MDCK cells expressing human OAT1.
|
|
pubmed:affiliation |
Division of Basic Medical Sciences, Mercer University, School of Medicine, Macon, Georgia 31207, USA. zalups_rk@mercer.edu
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, N.I.H., Extramural
|
