Source:http://linkedlifedata.com/resource/pubmed/id/16162257
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
10
|
| pubmed:dateCreated |
2005-9-15
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| pubmed:abstractText |
To supplement the traditional ICHD-2 diagnosis for migraine with aura (MA) we developed a diagnostic scale for migraine aura that quantifies the importance of the cardinal characteristics of MA. Since more than 99% of MA patients have visual aura, we developed for simplicity a Visual Aura Rating Scale (VARS). In total 427 patients with MA (ICHD-2) or nonaura visual disturbances were diagnosed in a validated semistructured interview by a trained physician. The patients were separated into a derivation sample and a validation sample. By regression analysis we identified the visual aura characteristics associated with MA in the derivation sample. Based on the identified characteristics we developed VARS and derived a predictive VARS score which was tested in the validation sample. The VARS score is the weighted sum of the presence of five visual symptom characteristics: duration 5-60 min (3 points), develops gradually > or = 5 min (2 points), scotoma (2 points), zig-zag lines (2 points), and unilateral (1 point). The maximum score is 10 points. A VARS score of 5 or more diagnosed MA with a sensitivity of 96% (95% CI 92-99%) and a specificity of 98%(95% CI 95-100%) in the derivation sample, and a sensitivity of 91% (95% CI 86-95%) and a specificity of 96% (95% CI 91-100%) in the validation sample. VARS adds evidence based weights to a number of clearly specified characteristics; it is easy to learn, apply and teach and may therefore be a valuable addition to traditional ICHD-2 diagnosis.
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| pubmed:language |
eng
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| pubmed:journal | |
| pubmed:citationSubset |
IM
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| pubmed:status |
MEDLINE
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| pubmed:month |
Oct
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| pubmed:issn |
0333-1024
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| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
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| pubmed:owner |
NLM
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| pubmed:authorsComplete |
Y
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| pubmed:pagination |
801-10
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| pubmed:dateRevised |
2008-2-11
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| pubmed:meshHeading |
pubmed-meshheading:16162257-Adolescent,
pubmed-meshheading:16162257-Adult,
pubmed-meshheading:16162257-Aged,
pubmed-meshheading:16162257-Aged, 80 and over,
pubmed-meshheading:16162257-Causality,
pubmed-meshheading:16162257-Child,
pubmed-meshheading:16162257-Comorbidity,
pubmed-meshheading:16162257-Female,
pubmed-meshheading:16162257-Humans,
pubmed-meshheading:16162257-Incidence,
pubmed-meshheading:16162257-Male,
pubmed-meshheading:16162257-Middle Aged,
pubmed-meshheading:16162257-Migraine with Aura,
pubmed-meshheading:16162257-Prognosis,
pubmed-meshheading:16162257-Reproducibility of Results,
pubmed-meshheading:16162257-Sensitivity and Specificity,
pubmed-meshheading:16162257-Severity of Illness Index,
pubmed-meshheading:16162257-Vision Disorders,
pubmed-meshheading:16162257-Vision Tests
|
| pubmed:year |
2005
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| pubmed:articleTitle |
The Visual Aura Rating Scale (VARS) for migraine aura diagnosis.
|
| pubmed:affiliation |
Danish Headache Center, University of Copenhagen, and Department of Neurology, Glostrup Hospital, Nordre Ringvej 57, DK-2600 Glostrup, Denmark. kirchmann@dadlnet.dk
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| pubmed:publicationType |
Journal Article,
Clinical Trial,
Research Support, Non-U.S. Gov't,
Validation Studies
|