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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
15-16
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pubmed:dateCreated |
2005-9-14
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pubmed:abstractText |
Meningeal melanocytoma refers to the uncommon clinical appearance of a generally benign tumour deriving from leptomeningeal melanocytes. Meningeal spread of this tumour is very rarely observed. We present the case of a 38-year-old man with meningeal melanocytoma of the cerebello-pontine angle, who showed a biphasic course of this disease, with a stable period followed by a steady progress within few months. After surgical resection of the melancytoma in the left skull base and of a first local recurrence five years later, a second local recurrence occurred 6 years after diagnosis, with intracerebral and spinal meningeal seeding. This tumor did not respond to a combined radiochemotherapy including oral temozolomide, and the patient died 5 months after starting treatment for this relapse. Secondary malignisation of the melancytoma is suggested.
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pubmed:language |
ger
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0043-5341
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
155
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
360-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16160923-Administration, Oral,
pubmed-meshheading:16160923-Adult,
pubmed-meshheading:16160923-Antineoplastic Agents, Alkylating,
pubmed-meshheading:16160923-Arachnoid,
pubmed-meshheading:16160923-Cerebellar Diseases,
pubmed-meshheading:16160923-Cerebellar Neoplasms,
pubmed-meshheading:16160923-Cerebellopontine Angle,
pubmed-meshheading:16160923-Combined Modality Therapy,
pubmed-meshheading:16160923-Dacarbazine,
pubmed-meshheading:16160923-Diagnosis, Differential,
pubmed-meshheading:16160923-Disease Progression,
pubmed-meshheading:16160923-Humans,
pubmed-meshheading:16160923-Magnetic Resonance Imaging,
pubmed-meshheading:16160923-Male,
pubmed-meshheading:16160923-Melanocytes,
pubmed-meshheading:16160923-Melanoma,
pubmed-meshheading:16160923-Meningeal Neoplasms,
pubmed-meshheading:16160923-Meninges,
pubmed-meshheading:16160923-Neoplasm Recurrence, Local,
pubmed-meshheading:16160923-Neoplasm Seeding,
pubmed-meshheading:16160923-Pia Mater,
pubmed-meshheading:16160923-Radiotherapy Dosage,
pubmed-meshheading:16160923-Time Factors
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pubmed:year |
2005
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pubmed:articleTitle |
[Spinal and cerebral leptomeningeal seeding from a melanocytoma of the cerebello-pontine angle].
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pubmed:affiliation |
Neurologische Universitätsklinik Regensburg, Deutschland. horst.koch@medbo.de
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pubmed:publicationType |
Journal Article,
English Abstract,
Case Reports
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